---
title: Project PROVOC
description: Project PROVOC is a research study investigating how the brains of people with OCD work by comparing them to the brains of people with either a specific phobia.
image: https://www.butler.org/hubfs/-%20BUTLER/ButlerResearchStudy.jpg
---

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![<span id=](https://www.butler.org/hubfs/-%20BUTLER/ButlerResearchStudy.jpg)Project PROVOC" class="bg-img" fetchpriority="high" loading="eager" decoding="async">

# Project PROVOC

#### Study Information:

Project PROVOC is a research study investigating differences in brain circuitry between people with OCD and those with no history of psychiatric diagnosis. This research could lead to a better understanding of how OCD works in the brain and pave the way for new or improved OCD treatments.

#### Eligibility Criteria:

- Men and women aged 18-65 years.
- Ability to travel to Butler Hospital for study visit(s).
- Ability to attend virtual visits on the computer over the internet.
- You fall into one of these groups:
  
  1. You have OCD.
  
  2. You have no history of being diagnosed with a psychiatric disorder.

#### Compensation/Reimbursement

Participants will be compensated a total of $100 in gift cards for participation in the full study.

#### **More Information/FAQ**

*What will happen if I join the study?*

First, you will attend two assessment visits. The first visit will be in-person or virtual, and the second will be virtual, about a week after the first visit. The day after your second visit, you will attend an in-person visit at Butler Hospital. During this visit, you will participate in a few tasks, including symptom provocation of OCD or general distress, while being monitored by our researchers and equipment.

*How will my symptoms be provoked?*

Symptoms of OCD or general distress will be provoked digitally (images displayed on a computer) and through gradual in-person exposure to distressing objects. The distressing images and objects will be discussed and selected by yourself and a clinician to tailor the experience to you without causing too much distress. You will have the opportunity to stop the procedure at any time.

*How long will this take?*

All participants will undergo two assessment visits and an in-person visit over the span of 1-2 weeks. The first assessment visit will take 3-4 hours at most, the second will take about 1 hour, and the in-person visit will take 4-5 hours at most.

#### **Primary Principal Investigator**

Nicole McLaughlin, PhD

#### Contact Form

**Organization**  
Butler Hospital

**Area of Study**  
OCD

**Status**  
Active

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